Imidazole → 4-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)tetrahydro-2H-pyran-4-carbonitrile
Reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[Si:20]([CH3:21])([CH3:22])[Cl:23].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[OH:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[nH:24]1[cH:25][cH:26][n:27][cH:28]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14]#[N:15])[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:6][cH:7]1)[Si:20]([C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:21])[CH3:22]Participants
5
Sources & evidence
- ORD record
- ord-2a1f5c50845b463ab7a599489ac7ca82
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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