Tetrahydrofuran → 4-Chloro-2-(4-hydroxybutyl)-6-morpholinopyrimidine

HRID 153572Notes

Reaction equation

HRID 153572 reaction equation
[CH2:23]([Al+:24][CH2:25][CH:26]([CH3:27])[CH3:28])[CH:29]([CH3:30])[CH3:31].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[Cl:1][c:2]1[n:3][c:4]([CH2:14][CH2:15][CH2:16][C:17](=[O:18])[O:19][CH2:20][CH3:21])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:7]1.[H-:22]>>[Cl:1][c:2]1[n:3][c:4]([CH2:14][CH2:15][CH2:16][CH2:17][OH:18])[n:5][c:6]([N:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 166653HydrideHCID 16686348Bis(2-methylpropyl)alumanyliumHCID 220469094-Chloro-2-(4-ethoxy-4-oxo-butyl)-6-morpholinopyrimidine

Product 1

HCID 220469294-Chloro-2-(4-hydroxybutyl)-6-morpholinopyrimidine

Sources & evidence

ORD record
ord-02f94ac6b6bb4be1ad48cdba033d40db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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