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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 153575Generated: October 27, 2026

Dichloromethane → N-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-7-{3-[4-(2-fluoroethyl)piperazin-1-yl]propoxy}-6-methoxyquinazolin-4-amine

https://huagongshe.com/reaction/153575

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant2-MethoxyethanolHCID 8019—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(2-Fluoroethyl)piperazineHCID 21082672—
ReactantN-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-7-(3-chloropropoxy)-6-methoxyquinazolin-4-amineHCID 68882624—
ProductN-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-7-{3-[4-(2-fluoroethyl)piperazin-1-yl]propoxy}-6-methoxyquinazolin-4-amineHCID 11758051—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-85de8b7a420b4a2ea7e9959f3932295f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)