Dimethyl Sulfoxide → rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid (5-carbamoyl-thiophen-2-yl)-amide
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([NH:8][C:9](=[O:10])[CH:11]2[CH:12]([c:31]3[c:32]([F:38])[c:33]([Cl:37])[cH:34][cH:35][cH:36]3)[C:13]3([C:14](=[O:23])[NH:15][c:16]4[cH:17][c:18]([Cl:22])[cH:19][cH:20][c:21]43)[CH:24]([CH2:26][C:27]([CH3:28])([CH3:29])[CH3:30])[NH:25]2)[s:7]1.[CH3:43][S:44]([CH3:45])=[O:46].[Na+:42].[OH-:41].[OH:39][OH:40]>>[C:1]([NH2:2])([c:3]1[cH:4][cH:5][c:6]([NH:8][C:9](=[O:10])[CH:11]2[CH:12]([c:31]3[c:32]([F:38])[c:33]([Cl:37])[cH:34][cH:35][cH:36]3)[C:13]3([C:14](=[O:23])[NH:15][c:16]4[cH:17][c:18]([Cl:22])[cH:19][cH:20][c:21]43)[CH:24]([CH2:26][C:27]([CH3:28])([CH3:29])[CH3:30])[NH:25]2)[s:7]1)=[O:39]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1ef11ce1c6764deca6866be3b9c85b36
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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