Trifluoroacetic acid → 1-Ethyl-5,6,8-trifluoro-3-hydroxy-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dione
Reaction equation
[B+3:52].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][n:9]1[c:10](=[O:30])[n:11]([CH2:28][CH3:29])[c:12]2[c:13]([F:27])[c:14]([N:22]3[CH2:23][CH2:24][CH2:25][CH2:26]3)[c:15]([F:21])[c:16]([F:20])[c:17]2[c:18]1=[O:19].[F:31][C:32]([F:33])([F:34])[C:35]([O-:36])=[O:37].[F:38][C:39]([F:40])([F:41])[C:42]([O-:43])=[O:44].[F:45][C:46]([F:47])([F:48])[C:49]([O-:50])=[O:51].[OH:53][C:54]([C:55]([F:56])([F:57])[F:58])=[O:59]>>[OH:8][n:9]1[c:10](=[O:30])[n:11]([CH2:28][CH3:29])[c:12]2[c:13]([F:27])[c:14]([N:22]3[CH2:23][CH2:24][CH2:25][CH2:26]3)[c:15]([F:21])[c:16]([F:20])[c:17]2[c:18]1=[O:19]Participants
5
Sources & evidence
- ORD record
- ord-faa094e7090e44eca29c27863338d3a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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