Dimethylformamide → (6-(2-Amino-6-oxo-1,6-dihydropurin-9-yl)-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl hydrogen sulfate

HRID 1536271Notes

Reaction equation

HRID 1536271 reaction equation
[NH2:10][c:11]1[nH:12][c:13](=[O:32])[c:14]2[n:15][cH:16][n:17]([CH:20]3[O:21][CH:22]([CH2:30][OH:31])[CH:23]4[O:24][C:25]([CH3:28])([CH3:29])[O:26][CH:27]34)[c:18]2[n:19]1.[O:33]=[CH:34][N:35]([CH3:36])[CH3:37].[O:5]=[CH:6][N:7]([CH3:8])[CH3:9].[S:1](=[O:2])(=[O:3])=[O:4]>>[S:1](=[O:2])(=[O:3])([OH:4])[O:31][CH2:30][CH:22]1[O:21][CH:20]([n:17]2[cH:16][n:15][c:14]3[c:13](=[O:32])[nH:12][c:11]([NH2:10])[n:19][c:18]32)[CH:27]2[CH:23]1[O:24][C:25]([CH3:28])([CH3:29])[O:26]2

Participants

4

Reactant 3

HCID 6228Dimethylformamide2×HCID 24682Sulfur trioxideHCID 1354241802-amino-9-[6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3H-purin-6-one

Product 1

HCID 136064682(6-(2-Amino-6-oxo-1,6-dihydropurin-9-yl)-2,2-dimethyl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl hydrogen sulfate

Sources & evidence

ORD record
ord-c85d80589e8448a0815cf788e010c89e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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