Dichloromethane → 6-[4-[4-[2-(4-Acetylpiperazin-1-yl)ethoxy]phenyl]piperidin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
Reaction equation
[CH3:75][CH2:76][CH2:77][CH2:78][CH2:79][CH2:80][CH3:81].[Cl:72][CH2:73][Cl:74].[F:1][C:2]([c:3]1[n:4][n:5][c:6]2[n:7]1[n:8][c:9]([N:12]1[CH2:13][CH2:14][CH:15]([c:18]3[cH:19][cH:20][c:21]([OH:24])[cH:22][cH:23]3)[CH2:16][CH2:17]1)[cH:10][cH:11]2)([F:25])[F:26].[N:58]([C:59]([O:60][CH:61]([CH3:62])[CH3:63])=[O:64])=[N:65][C:66]([O:67][CH:68]([CH3:69])[CH3:70])=[O:71].[OH:46][CH2:47][CH2:48][N:49]1[CH2:50][CH2:51][N:52]([C:55]([CH3:56])=[O:57])[CH2:53][CH2:54]1.[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[F:1][C:2]([c:3]1[n:4][n:5][c:6]2[n:7]1[n:8][c:9]([N:12]1[CH2:13][CH2:14][CH:15]([c:18]3[cH:19][cH:20][c:21]([O:24][CH2:47][CH2:48][N:49]4[CH2:50][CH2:51][N:52]([C:55]([CH3:56])=[O:57])[CH2:53][CH2:54]4)[cH:22][cH:23]3)[CH2:16][CH2:17]1)[cH:10][cH:11]2)([F:25])[F:26]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-29d637a631174ed3a090868f85be54fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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