N-methyl-2-pyrrolidone → N-[6-[(6-anilinopyrimidin-4-yl)amino]-2-pyridinyl]-4-(dimethylamino)but-2-enamide
Reaction equation
[CH3:22][N:23]([CH3:24])[CH2:25][CH:26]=[CH:27][C:28](=[O:29])[Cl:30].[CH3:31][N:32]1[CH2:33][CH2:34][CH2:35][C:36]1=[O:37].[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]([NH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[cH:14]2)[n:7]1>>[NH:1]([c:2]1[cH:3][cH:4][cH:5][c:6]([NH:8][c:9]2[n:10][cH:11][n:12][c:13]([NH:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[cH:14]2)[n:7]1)[C:28]([CH:27]=[CH:26][CH2:25][N:23]([CH3:22])[CH3:24])=[O:29]Participants
4
Sources & evidence
- ORD record
- ord-d169c138f4d5457ebf2ddb73833a6752
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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