Dimethylformamide → 3-bromopropyl Methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

HRID 1536887Notes

Reaction equation

HRID 1536887 reaction equation
[Br:29][CH2:30][CH2:31][CH2:32][OH:33].[CH3:1][C:2]1=[C:7]([C:8](=[O:9])[O:10][CH3:11])[CH:6]([c:12]2[cH:13][c:14]([N+:18](=[O:19])[O-:20])[cH:15][cH:16][cH:17]2)[C:5]([C:21](=[O:22])[OH:23])=[C:4]([CH3:24])[NH:3]1.[Cl:34][CH2:35][Cl:36].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[S:25]([Cl:26])([Cl:27])=[O:28]>>[CH3:1][C:2]1=[C:7]([C:8](=[O:9])[O:10][CH3:11])[CH:6]([c:12]2[cH:13][c:14]([N+:18](=[O:19])[O-:20])[cH:15][cH:16][cH:17]2)[C:5]([C:21](=[O:22])[O:33][CH2:32][CH2:31][CH2:30][Br:29])=[C:4]([CH3:24])[NH:3]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 123083-Bromo-1-propanolHCID 24386Thionyl ChlorideHCID 1733222,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester

Product 1

HCID 32742783-bromopropyl Methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

Sources & evidence

ORD record
ord-18bfe9675c234ddda20fb94dec621908
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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