Methane → rac-(2R,3R,4R,5s)-3-(3-chloro-phenyl)-4-(4-chloro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carboxylic acid (3-methanesulfonylamino-propyl)-amide
Reaction equation
[CH3:40][N:41]([c:42]1[cH:43][cH:44][cH:45][cH:46][n:47]1)[CH3:48].[CH4:39].[Cl:49][CH2:50][Cl:51].[NH2:1][CH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:7])[CH:8]1[NH:9][CH:10]([CH2:29][C:30]([CH3:31])([CH3:32])[CH3:33])[C:11]([C:20]#[N:21])([c:22]2[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[CH:12]1[c:13]1[cH:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]1.[S:34](=[O:35])(=[O:36])([Cl:37])[Cl:38]>>[NH:1]([CH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:7])[CH:8]1[NH:9][CH:10]([CH2:29][C:30]([CH3:31])([CH3:32])[CH3:33])[C:11]([C:20]#[N:21])([c:22]2[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]2)[CH:12]1[c:13]1[cH:14][c:15]([Cl:19])[cH:16][cH:17][cH:18]1)[S:34](=[O:35])(=[O:36])[CH3:40]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d8df203a564d4719be8536041def40c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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