Imidazole → N-[3-cyano-4-(4-hydroxypiperidin-1-yl)phenyl]-N-methylbenzo[b]thiophene-2-carboxamide
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([NH:16][C:17](=[O:18])[c:19]2[cH:20][c:21]3[c:22]([s:23]2)[cH:24][cH:25][cH:26][cH:27]3)[cH:6][cH:7][c:8]1[N:9]1[CH2:10][CH2:11][CH:12]([OH:15])[CH2:13][CH2:14]1.[C:28]([Si:29]([Cl:30])([CH3:31])[CH3:32])([CH3:33])([CH3:34])[CH3:35].[CH3:41][N:42]([CH3:43])[CH:44]=[O:45].[OH2:46].[nH:36]1[cH:37][cH:38][n:39][cH:40]1>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([N:16]([C:17](=[O:18])[c:19]2[cH:20][c:21]3[c:22]([s:23]2)[cH:24][cH:25][cH:26][cH:27]3)[CH3:28])[cH:6][cH:7][c:8]1[N:9]1[CH2:10][CH2:11][CH:12]([OH:15])[CH2:13][CH2:14]1Participants
6
Sources & evidence
- ORD record
- ord-ac1ffbf2875b4e378394c96bfe73ed62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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