Imidazole → (S)-tert-butyl 2-(2-cyanopyrrolidin-1-yl)-2-oxoethylcarbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][C:9](=[O:10])[N:11]1[CH:12]([C:16]([NH2:17])=[O:18])[CH2:13][CH2:14][CH2:15]1)=[O:19].[P:25]([Cl:26])([Cl:27])([Cl:28])=[O:29].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1.[nH:20]1[cH:21][cH:22][n:23][cH:24]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][C:9](=[O:10])[N:11]1[CH:12]([C:16]#[N:17])[CH2:13][CH2:14][CH2:15]1)=[O:19]Participants
5
Sources & evidence
- ORD record
- ord-f425bd5b439d4f84919588f02c45e029
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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