Toluene → 1-Methoxy-4-(4-methoxybenzylsulfanyl)-piperidine-4-carbonyl chloride

HRID 1537152Notes

Reaction equation

HRID 1537152 reaction equation
[CH3:1][O:2][N:3]1[CH2:4][CH2:5][C:6]([C:9](=[O:10])[OH:11])([S:12][CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[CH2:7][CH2:8]1.[CH3:22][N:23]([CH3:24])[CH:25]=[O:26].[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[S:27]([Cl:28])([Cl:29])=[O:30]>>[CH3:1][O:2][N:3]1[CH2:4][CH2:5][C:6]([C:9](=[O:10])[Cl:29])([S:12][CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[CH2:7][CH2:8]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 667939621-Methoxy-4-(4-methoxy-benzylsulfanyl)-piperidine-4-carboxylic acid

Product 1

HCID 866633001-Methoxy-4-(4-methoxybenzylsulfanyl)-piperidine-4-carbonyl chloride

Sources & evidence

ORD record
ord-aac9942ca2fc43498afc1790401c639d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…