Dichloromethane → N-[6-cyano-1-(1,3-thiazol-5-ylmethyl)-3,4-dihydro-2H-quinolin-3-yl]benzenesulfonamide

HRID 1537304Notes

Reaction equation

HRID 1537304 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[NH:9][CH2:8][CH:7]([NH:13][S:14](=[O:15])(=[O:16])[c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH2:6]2.[Cl:37][CH2:38][Cl:39].[F:30][C:31]([F:32])([F:33])[C:34]([OH:35])=[O:36].[s:23]1[cH:24][n:25][cH:26][c:27]1[CH:28]=[O:29]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[N:9]([CH2:28][c:27]1[s:23][cH:24][n:25][cH:26]1)[CH2:8][CH:7]([NH:13][S:14](=[O:15])(=[O:16])[c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH2:6]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 27735771,3-Thiazole-5-carbaldehydeHCID 17759418N-(6-Cyano-1,2,3,4-tetrahydroquinolin-3-yl)-benzenesulfonamide

Product 1

HCID 66757390N-[6-cyano-1-(1,3-thiazol-5-ylmethyl)-3,4-dihydro-2H-quinolin-3-yl]benzenesulfonamide

Sources & evidence

ORD record
ord-77a483cbf6d4412f9a956424bbdf4be1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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