Acetone → 3-bromo-4-[(2,4-difluorobenzyl)oxy]-1-(2,6-difluorophenyl)-5-(1,2-dihydroxyethyl)-6-methylpyridin-2(1H)-one
Reaction equation
[Br:1][c:2]1[c:3](=[O:29])[n:4](-[c:21]2[c:22]([F:28])[cH:23][cH:24][cH:25][c:26]2[F:27])[c:5]([CH3:20])[c:6]([CH:18]=[CH2:19])[c:7]1[O:8][CH2:9][c:10]1[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]1.[C:39](#[N:40])[CH3:41].[CH3:30][N+:31]1([O-:32])[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1.[CH3:42][C:43]([CH3:44])=[O:45].[OH2:38].[OH2:46]>>[Br:1][c:2]1[c:3](=[O:29])[n:4](-[c:21]2[c:22]([F:28])[cH:23][cH:24][cH:25][c:26]2[F:27])[c:5]([CH3:20])[c:6]([CH:18]([CH2:19][OH:38])[OH:46])[c:7]1[O:8][CH2:9][c:10]1[c:11]([F:17])[cH:12][c:13]([F:16])[cH:14][cH:15]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4d0d831c0c8c4dfb8bc2133db1d99d27
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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