Piconol → (RS)-[2,6-difluoro-4-(pyridin-2-ylmethoxy)-phenyl]-ethoxy-acetic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH:5]([O:6][CH2:7][CH3:8])[c:9]1[c:10]([F:17])[cH:11][c:12]([OH:16])[cH:13][c:14]1[F:15])=[O:18].[OH:19][CH2:20][c:21]1[n:22][cH:23][cH:24][cH:25][cH:26]1>>[CH2:1]([CH3:2])[O:3][C:4]([CH:5]([O:6][CH2:7][CH3:8])[c:9]1[c:10]([F:17])[cH:11][c:12]([O:16][CH2:20][c:21]2[n:22][cH:23][cH:24][cH:25][cH:26]2)[cH:13][c:14]1[F:15])=[O:18]Participants
3
Sources & evidence
- ORD record
- ord-fc640c4a46f540e9bd1c24c3322ad738
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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