Bicarbonate Ion → 2-chloro-3-(1-cyano-1-methylethoxy)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}amino)-2-fluorophenyl]benzamide
Reaction equation
[C:41](=[O:42])([O-:43])[OH:44].[CH3:46][N:47]([CH3:48])[C:49](=[O:50])[CH3:51].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[Cl:6])[cH:7][cH:8][cH:9][c:10]1[O:11][C:12]([CH3:13])([CH3:14])[C:15]#[N:16].[NH2:17][c:18]1[cH:19][c:20]([NH:25][c:26]2[cH:27][cH:28][c:29]3[c:30]([n:31]2)[s:32][c:33]([NH:35][C:36](=[O:37])[CH:38]2[CH2:39][CH2:40]2)[n:34]3)[cH:21][cH:22][c:23]1[F:24].[Na+:45]>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[NH:17][c:18]2[cH:19][c:20]([NH:25][c:26]3[cH:27][cH:28][c:29]4[c:30]([n:31]3)[s:32][c:33]([NH:35][C:36](=[O:37])[CH:38]3[CH2:39][CH2:40]3)[n:34]4)[cH:21][cH:22][c:23]2[F:24])[cH:7][cH:8][cH:9][c:10]1[O:11][C:12]([CH3:13])([CH3:14])[C:15]#[N:16]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-21fbe6ea08f644b2addb7e4aad3a95bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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