Tetrahydrofuran → 4-(2-chloro-4-iodoanilino)-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]-1,3-dimethyl-2,6-dioxopyrimidine-5-carboxamide

HRID 1537732Notes

Reaction equation

HRID 1537732 reaction equation
[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:29][C:30]1([CH3:38])[O:31][CH2:32][CH:33]([CH2:35][O:36][NH2:37])[O:34]1.[Cl:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:21])[O:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1>>[Cl:1][c:2]1[c:3]([NH:9][c:10]2[c:11]([C:20](=[O:21])[NH:37][O:36][CH2:35][CH:33]3[CH2:32][O:31][C:30]([CH3:29])([CH3:38])[O:34]3)[c:12](=[O:19])[n:13]([CH3:18])[c:14](=[O:17])[n:15]2[CH3:16])[cH:4][cH:5][c:6]([I:8])[cH:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 10240948O-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]hydroxylamineHCID 25108891Phenyl 6-(2-chloro-4-iodophenylamino)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Product 1

HCID 870798114-(2-chloro-4-iodoanilino)-N-[(2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]-1,3-dimethyl-2,6-dioxopyrimidine-5-carboxamide

Sources & evidence

ORD record
ord-76f6820d63414711a07d25d69a209dd0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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