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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1537875Generated: October 27, 2026

Tetrahydrofuran → 5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-prop-2-enyl-1-(1,1,1-trifluoro-2-hydroxypentan-3-yl)piperidin-2-one

https://huagongshe.com/reaction/1537875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
Reactant2-[3-(3-Chlorophenyl)-2-(4-chlorophenyl)-6-oxo-5-prop-2-enylpiperidin-1-yl]butanalHCID 76834750—
Product5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-prop-2-enyl-1-(1,1,1-trifluoro-2-hydroxypentan-3-yl)piperidin-2-oneHCID 76834620—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (1/10)
ORD IDord-3d31c7fb3fac4d3c9e19843fe5b41c61
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (1/10)