Tetrahydrofuran → 5-(3-Chlorophenyl)-6-(4-chlorophenyl)-3-prop-2-enyl-1-(1,1,1-trifluoro-2-hydroxypentan-3-yl)piperidin-2-one
Reaction equation
[CH2:1]([CH:2]=[CH2:3])[CH:4]1[C:5](=[O:29])[N:6]([CH:24]([CH:25]=[O:26])[CH2:27][CH3:28])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1.[CH2:62]1[O:63][CH2:64][CH2:65][CH2:66]1.[CH3:30][Si:31]([C:32]([F:33])([F:34])[F:35])([CH3:36])[CH3:37].[CH3:39][CH2:40][CH2:41][CH2:42][N+:43]([CH2:44][CH2:45][CH2:46][CH3:47])([CH2:48][CH2:49][CH2:50][CH3:51])[CH2:52][CH2:53][CH2:54][CH3:55].[CH3:56][CH2:57][O:58][C:59]([CH3:60])=[O:61].[F-:38]>>[CH2:1]([CH:2]=[CH2:3])[CH:4]1[C:5](=[O:29])[N:6]([CH:24]([CH:25]([OH:26])[C:32]([F:33])([F:34])[F:35])[CH2:27][CH3:28])[CH:7]([c:17]2[cH:18][cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[CH:8]([c:10]2[cH:11][c:12]([Cl:16])[cH:13][cH:14][cH:15]2)[CH2:9]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-3d31c7fb3fac4d3c9e19843fe5b41c61
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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