Tetrahydrofuran → 3-[1-[4-(Trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propan-1-ol
Reaction equation
[Br:22][CH2:23][CH2:24][CH2:25][OH:26].[CH2:17]1[CH2:18][CH2:19][CH2:20][O:21]1.[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]23[CH2:10][NH:11][CH2:12][CH:13]2[CH2:14]3)[cH:7][cH:8]1)([F:15])[F:16]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([C:9]23[CH2:10][N:11]([CH2:18][CH2:19][CH2:20][OH:21])[CH2:12][CH:13]2[CH2:14]3)[cH:7][cH:8]1)([F:15])[F:16]Participants
4
Sources & evidence
- ORD record
- ord-e26dccfa3c2945c1b13c64f2e96743e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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