Potassium Cation → Gamma-(aminocarbonyl)-4-[[4-(bromomethyl)phenyl]methoxy]-1,3-dihydro-1-oxo-2h-isoindole-2-butanoic acid methyl ester

HRID 1538376Notes

Reaction equation

HRID 1538376 reaction equation
[Br:22][CH2:23][c:24]1[cH:25][cH:26][c:27]([CH2:30][Br:31])[cH:28][cH:29]1.[C:32](=[O:33])([O-:34])[O-:35].[CH3:38][C:39]#[N:40].[K+:36].[K+:37].[NH2:1][C:2]([CH:3]([CH2:4][CH2:5][C:6](=[O:7])[O:8][CH3:9])[N:10]1[C:11](=[O:20])[c:12]2[cH:13][cH:14][cH:15][c:16]([OH:19])[c:17]2[CH2:18]1)=[O:21]>>[NH2:1][C:2]([CH:3]([CH2:4][CH2:5][C:6](=[O:7])[O:8][CH3:9])[N:10]1[C:11](=[O:20])[c:12]2[cH:13][cH:14][cH:15][c:16]([O:19][CH2:30][c:27]3[cH:26][cH:25][c:24]([CH2:23][Br:22])[cH:29][cH:28]3)[c:17]2[CH2:18]1)=[O:21]

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 693351,4-Bis(bromomethyl)benzeneHCID 58389139Methyl 5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoate

Product 1

HCID 58388934Gamma-(aminocarbonyl)-4-[[4-(bromomethyl)phenyl]methoxy]-1,3-dihydro-1-oxo-2h-isoindole-2-butanoic acid methyl ester

Sources & evidence

ORD record
ord-c79eddb02fb2478d8a2d34008ecd17b8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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