Dichloromethane → 2-Nitro-4-(1-piperidin-4-ylmethoxy)5-methoxybenzonitrile

HRID 1538377Notes

Reaction equation

HRID 1538377 reaction equation
[Cl:36][CH2:37][Cl:38].[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35].[N+:1](=[O:2])([O-:3])[c:4]1[c:5]([C:6]#[N:7])[cH:8][c:9]([O:27][CH3:28])[c:10]([O:12][CH2:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:18][CH2:19]2)[cH:11]1>>[N+:1](=[O:2])([O-:3])[c:4]1[c:5]([C:6]#[N:7])[cH:8][c:9]([O:27][CH3:28])[c:10]([O:12][CH2:13][CH:14]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[cH:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 223496402-Nitro-4-((1-tert-butyloxycarbonylpiperidin-4-yl)methoxy)-5-methoxybenzonitrile

Product 1

HCID 223496252-Nitro-4-(1-piperidin-4-ylmethoxy)5-methoxybenzonitrile

Sources & evidence

ORD record
ord-1e47d5204521496ea27e213698c04cc0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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