Toluene → N-Cbz-L-valyl-L-proline

HRID 1538640Notes

Reaction equation

HRID 1538640 reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13]([CH:14]1[N:15]([C:19]([CH:20]([NH:21][C:22](=[O:23])[O:24][CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[CH:32]([CH3:33])[CH3:34])=[O:35])[CH2:16][CH2:17][CH2:18]1)=[O:36].[CH2:44]([Cl:45])[Cl:46].[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[O:12]=[C:13]([CH:14]1[N:15]([C:19]([CH:20]([NH:21][C:22](=[O:23])[O:24][CH2:25][c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[CH:32]([CH3:33])[CH3:34])=[O:35])[CH2:16][CH2:17][CH2:18]1)[OH:36]

Participants

5

Reactant 4

HCID 1140TolueneHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178449693HCID 178449693, compound

Product 1

HCID 12799361N-Cbz-L-valyl-L-proline

Sources & evidence

ORD record
ord-bfbeccb34ff048fabb65b8d49be23785
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…