Methanol → (5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-(2-cyclopropylmethoxy-3-hydroxy-phenyl)-methanone

HRID 1538885Notes

Reaction equation

HRID 1538885 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:27][CH2:28][CH:29]2[CH2:30][CH2:31]2)[c:11]([C:15](=[O:16])[c:17]2[cH:18][nH:19][c:20]3[n:21][cH:22][c:23]([Cl:26])[cH:24][c:25]23)[cH:12][cH:13][cH:14]1.[CH3:34][OH:35].[H:32][H:33].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[OH:8][c:9]1[c:10]([O:27][CH2:28][CH:29]2[CH2:30][CH2:31]2)[c:11]([C:15](=[O:16])[c:17]2[cH:18][nH:19][c:20]3[n:21][cH:22][c:23]([Cl:26])[cH:24][c:25]23)[cH:12][cH:13][cH:14]1

Participants

5

Reactant 4

HCID 887MethanolHCID 8028TetrahydrofuranHCID 59803895[3-benzyloxy-2-cyclopropylmethoxy-phenyl]-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanoneHCID 178418361HCID 178418361, compound

Product 1

HCID 59803815(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-(2-cyclopropylmethoxy-3-hydroxy-phenyl)-methanone

Sources & evidence

ORD record
ord-1aa6bc7e2b5b4d66b1aece375b9c301c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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