Tetrahydrofuran → Methanesulfonic acid 6-[1-(3-trifluoromethyl-phenylcarbamoyl)-2,3-dihydro-1H-indol-5-yloxy]-pyrimidin-4-ylmethyl ester
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:32][S:33]([Cl:34])(=[O:35])=[O:36].[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][c:15]3[cH:16][c:17]([O:21][c:22]4[n:23][cH:24][n:25][c:26]([CH2:28][OH:29])[cH:27]4)[cH:18][cH:19][c:20]32)[cH:6][cH:7][cH:8]1)([F:30])[F:31]>>[F:1][C:2]([c:3]1[cH:4][c:5]([NH:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][c:15]3[cH:16][c:17]([O:21][c:22]4[n:23][cH:24][n:25][c:26]([CH2:28][O:29][S:33]([CH3:32])(=[O:35])=[O:36])[cH:27]4)[cH:18][cH:19][c:20]32)[cH:6][cH:7][cH:8]1)([F:30])[F:31]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-a96153075ceb4631a041da3587535233
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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