HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → HCID 131728175, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | Clopidogrel | HCID 60606 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 131728175 | HCID 131728175 | — |
Reaction Steps
Clopidogrel base was dissolved in methanol to obtain a clear solution. Methanesulfonic acid was added to the solution at 20° C. The reaction mixture was heated to reflux temperature for 2 to 10 hrs. The solvent was evaporated to dryness under reduced pressure to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732608B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-22cad0c2ae7a45ccb8f724d674d8204a |
| Source note | uspto-grants-2010_06 |