Pyridine → 3-{1-[Bis(4-chlorophenyl)methyl]azetidin-3-ylidene}-3-(3,5-difluorophenyl)propanenitrile
Reaction equation
[CH3:31][S:32]([O:33][S:34]([CH3:35])(=[O:36])=[O:37])(=[O:38])=[O:39].[CH3:49][C:50]#[N:51].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([N:9]2[CH2:10][C:11](=[C:13]([CH2:14][OH:15])[c:16]3[cH:17][c:18]([F:23])[cH:19][c:20]([F:22])[cH:21]3)[CH2:12]2)[c:24]2[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[cH:6][cH:7]1.[Na:40][C:41]#[N:42].[cH:43]1[cH:44][cH:45][n:46][cH:47][cH:48]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([N:9]2[CH2:10][C:11](=[C:13]([CH2:14][C:41]#[N:42])[c:16]3[cH:17][c:18]([F:23])[cH:19][c:20]([F:22])[cH:21]3)[CH2:12]2)[c:24]2[cH:25][cH:26][c:27]([Cl:30])[cH:28][cH:29]2)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8e8e7a63cf674baeb9ab24e81cb46694
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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