Hydrogen Bromide → N-(2-cyclopropylimidazo[1,2-a]pyridin-6-yl)-4''-(trifluoromethyl)biphenyl-4-carboxamide

HRID 1539217Notes

Reaction equation

HRID 1539217 reaction equation
[BrH:1].[CH:2]1([c:5]2[n:6][c:7]3[n:8]([cH:9][c:10]([N+:13]([O-:14])=[O:15])[cH:11][cH:12]3)[cH:16]2)[CH2:3][CH2:4]1.[F:17][C:18]([c:19]1[cH:20][cH:21][c:22](-[c:25]2[cH:26][cH:27][c:28]([C:31](=[O:32])[OH:33])[cH:29][cH:30]2)[cH:23][cH:24]1)([F:34])[F:35]>>[CH:2]1([c:5]2[n:6][c:7]3[n:8]([cH:9][c:10]([NH:13][C:31]([c:28]4[cH:27][cH:26][c:25](-[c:22]5[cH:21][cH:20][c:19]([C:18]([F:17])([F:34])[F:35])[cH:24][cH:23]5)[cH:30][cH:29]4)=[O:32])[cH:11][cH:12]3)[cH:16]2)[CH2:3][CH2:4]1

Participants

4

Reactant 3

HCID 260Hydrogen BromideHCID 27827194'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acidHCID 231205182-Cyclopropyl-6-nitroimidazo[1,2-a]pyridine

Product 1

HCID 23120576N-(2-cyclopropylimidazo[1,2-a]pyridin-6-yl)-4''-(trifluoromethyl)biphenyl-4-carboxamide

Sources & evidence

ORD record
ord-af923e6ec32643da90445c22765c4c30
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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