Dichloromethane → Morpholin-3-ylmethyl 4-(2,4-difluorophenyl)piperazine-1-carboxylate

HRID 1539394Notes

Reaction equation

HRID 1539394 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([CH2:14][O:15][C:16](=[O:17])[N:18]2[CH2:19][CH2:20][N:21]([c:24]3[c:25]([F:31])[cH:26][c:27]([F:30])[cH:28][cH:29]3)[CH2:22][CH2:23]2)[CH2:10][O:11][CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:39][CH2:40][Cl:41].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38]>>[NH:8]1[CH:9]([CH2:14][O:15][C:16](=[O:17])[N:18]2[CH2:19][CH2:20][N:21]([c:24]3[c:25]([F:31])[cH:26][c:27]([F:30])[cH:28][cH:29]3)[CH2:22][CH2:23]2)[CH2:10][O:11][CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 669345373-[4-(2,4-Difluoro-phenyl)-piperazine-1-carbonyloxymethyl]-morpholine-4-carboxylic acid tert-butyl ester

Product 1

HCID 42634521Morpholin-3-ylmethyl 4-(2,4-difluorophenyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-e75ce97088d44465be361be2eb2cdecf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…