Ammonia → N,N-Didesmethylvenlafaxine

HRID 1539415Notes

Reaction equation

HRID 1539415 reaction equation
[C:1](#[N:2])[CH:3]([C:4]1([OH:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]1)[c:11]1[cH:12][cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]1.[CH2:19]([OH:20])[CH3:21].[NH3:22].[Rh:23]>>[CH2:1]([NH2:2])[CH:3]([C:4]1([OH:10])[CH2:5][CH2:6][CH2:7][CH2:8][CH2:9]1)[c:11]1[cH:12][cH:13][c:14]([O:17][CH3:18])[cH:15][cH:16]1

Participants

5

Reactant 4

HCID 222AmmoniaHCID 702EthanolHCID 23948RhodiumHCID 9899621(1-Hydroxycyclohexyl)(4-methoxyphenyl)acetonitrile

Product 1

HCID 9795857N,N-Didesmethylvenlafaxine

Sources & evidence

ORD record
ord-e8b918110e904d46a4e3d50e1e09c005
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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