Dichloromethane → 4-[5-(3-Methyl-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]-1-(phenylsulfonyl)piperidin-4-ol
Reaction equation
[CH3:1][c:2]1[cH:3][c:4](-[c:19]2[cH:20][n:21][c:22]([C:24]3([OH:30])[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]3)[s:23]2)[cH:5][c:6]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[n:14]2)[cH:7]1.[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:50][CH2:51][Cl:52].[c:40]1([S:46](=[O:47])(=[O:48])[Cl:49])[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[CH3:1][c:2]1[cH:3][c:4](-[c:19]2[cH:20][n:21][c:22]([C:24]3([OH:30])[CH2:25][CH2:26][N:27]([S:46]([c:40]4[cH:41][cH:42][cH:43][cH:44][cH:45]4)(=[O:47])=[O:48])[CH2:28][CH2:29]3)[s:23]2)[cH:5][c:6]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[n:14]2)[cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5d973a0d855e47b3ae2d1bdc142decab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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