Ethanol → 7-[1-(2,6-Dimethylpyridin-4-yl)-4-ethoxycarbonylpiperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid benzyl ester
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][c:13]2[cH:14][c:15]([O:21][CH2:22][C:23]3([C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]3)[cH:16][cH:17][c:18]2[CH2:19][CH2:20]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:50][CH2:51][OH:52].[Cl:41][c:42]1[cH:43][c:44]([CH3:49])[n:45][c:46]([CH3:48])[cH:47]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH2:12][c:13]2[cH:14][c:15]([O:21][CH2:22][C:23]3([C:29](=[O:30])[O:31][CH2:32][CH3:33])[CH2:24][CH2:25][N:26]([c:42]4[cH:43][c:44]([CH3:49])[n:45][c:46]([CH3:48])[cH:47]4)[CH2:27][CH2:28]3)[cH:16][cH:17][c:18]2[CH2:19][CH2:20]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-ba04c38c14924d2ca4245c575421ee4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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