4-(Dimethylamino)pyridine → 1-(3-(2-Fluoropropan-2-yl)isoxazol-5-yl)-3-(3-(6-methoxy-7-(2-morpholinoethoxy)quinazolin-4-yloxy)phenyl)urea
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:22][c:23]3[cH:24][c:25]([NH2:26])[cH:27][cH:28][cH:29]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1.[CH3:49][N:50]([CH3:51])[c:52]1[cH:53][cH:54][n:55][cH:56][cH:57]1.[F:30][C:31]([CH3:32])([CH3:33])[c:34]1[n:35][o:36][c:37]([NH:39][C:40]([O:41][c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)=[O:42])[cH:38]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([O:22][c:23]3[cH:24][c:25]([NH:26][C:40]([NH:39][c:37]4[o:36][n:35][c:34]([C:31]([F:30])([CH3:32])[CH3:33])[cH:38]4)=[O:41])[cH:27][cH:28][cH:29]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-65fa5992b6b348a78e376ceefec86960
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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