Hydrochloric Acid → N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2-(morpholin-4-ylmethyl)-1,3-thiazol-4-yl]methyl}oxy)quinazolin-4-amine
Reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[CH3:44][C:45]([O:46][I:47]1([O:57][C:58]([CH3:59])=[O:60])([O:61][C:62]([CH3:63])=[O:64])[c:48]2[c:49]([cH:50][cH:51][cH:52][cH:53]2)[C:54](=[O:55])[O:56]1)=[O:65].[Cl:16][c:17]1[cH:18][c:19]([NH:24][c:25]2[n:26][cH:27][n:28][c:29]3[cH:30][c:31]([OH:37])[c:32]([O:35][CH3:36])[cH:33][c:34]23)[cH:20][cH:21][c:22]1[Cl:23].[Cl:2][CH2:3][c:4]1[n:5][c:6]([CH2:9][N:10]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[s:7][cH:8]1.[ClH:1].[K+:42].[K+:43]>>[CH2:3]([c:4]1[n:5][c:6]([CH2:9][N:10]2[CH2:11][CH2:12][O:13][CH2:14][CH2:15]2)[s:7][cH:8]1)[O:37][c:31]1[cH:30][c:29]2[n:28][cH:27][n:26][c:25]([NH:24][c:19]3[cH:18][c:17]([Cl:16])[c:22]([Cl:23])[cH:21][cH:20]3)[c:34]2[cH:33][c:32]1[O:35][CH3:36]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d8c024a5dc294cfe825531448d014380
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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