Dichloromethane → Trifluoroacetic acid

HRID 1540176Notes

Reaction equation

HRID 1540176 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][O:6][CH:7]([CH:8]1[CH2:9][N:10]([C:14](=[O:15])[NH:16][CH:17]([CH2:18][NH:19][C:20](=[O:21])[O:22][CH2:23][CH2:24][Si:25]([CH3:26])([CH3:27])[CH3:28])[CH2:29][CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]2)[CH2:11][CH2:12][CH2:13]1)[c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[Cl:49][CH2:50][Cl:51].[F:42][C:43]([C:44](=[O:45])[OH:46])([F:47])[F:48]>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][O:6][CH:7]([CH:8]1[CH2:9][N:10]([C:14](=[O:15])[NH:16][CH:17]([CH2:18][NH2:19])[CH2:29][CH:30]2[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]2)[CH2:11][CH2:12][CH2:13]1)[c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1.[F:42][C:43]([C:44](=[O:45])[OH:46])([F:47])[F:48]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 178495547HCID 178495547, compound

Product 2

HCID 6422Trifluoroacetic acidHCID 11626474N-(1-amino-3-cyclohexylpropan-2-yl)-3-[3-methoxypropoxy(phenyl)methyl]piperidine-1-carboxamide

Sources & evidence

ORD record
ord-aea9bb5a0f7147279ac0b99fb22d949a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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