Dichloromethane → N-(5-amino-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide

HRID 1540193Notes

Reaction equation

HRID 1540193 reaction equation
[Cl:35][CH2:36][Cl:37].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[n:8]1[cH:9][c:10]([C:17](=[O:18])[NH:19][c:20]2[cH:21][c:22]([NH:27][C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[cH:23][cH:24][c:25]2[CH3:26])[n:11]2[c:12]1[cH:13][cH:14][cH:15][cH:16]2>>[n:8]1[cH:9][c:10]([C:17](=[O:18])[NH:19][c:20]2[cH:21][c:22]([NH2:27])[cH:23][cH:24][c:25]2[CH3:26])[n:11]2[c:12]1[cH:13][cH:14][cH:15][cH:16]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 71280675Tert-butyl 3-(imidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenylcarbamate

Product 1

HCID 86677450N-(5-amino-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide

Sources & evidence

ORD record
ord-13e75e4d95394c08a171c7a7414ce9ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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