Dichloromethane → tert-Butyl (6-chloro-2-oxo-2,3-dihydrobenzimidazol-1-yl)acetate

HRID 1540446Notes

Reaction equation

HRID 1540446 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH2:8][n:9]1[c:10](=[O:26])[n:11]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[c:12]2[c:13]1[cH:14][c:15]([Cl:18])[cH:16][cH:17]2.[Cl:34][CH2:35][Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[CH2:8][n:9]1[c:10](=[O:26])[nH:11][c:12]2[c:13]1[cH:14][c:15]([Cl:18])[cH:16][cH:17]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 66754580Tert-butyl 3-tert-butoxycarbonylmethyl-5-chloro-2-oxo-2,3-dihydrobenzimidazole-1-carboxylate

Product 1

HCID 86642492tert-Butyl (6-chloro-2-oxo-2,3-dihydrobenzimidazol-1-yl)acetate

Sources & evidence

ORD record
ord-d3ccfb57074145b480c3105337dfdc1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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