Imidazole → 5-TBDMS-5-I-2-dC

HRID 1540661Notes

Reaction equation

HRID 1540661 reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[Si:27]([CH3:28])([CH3:29])[Cl:30].[I:1][c:2]1[c:3]([NH2:17])[n:4][c:5](=[O:16])[n:6]([CH:7]2[CH2:8][CH:9]([OH:10])[CH:11]([CH2:12][OH:13])[O:14]2)[cH:15]1.[O:31]=[CH:32][N:33]([CH3:34])[CH3:35].[nH:18]1[cH:19][cH:20][n:21][cH:22]1>>[I:1][c:2]1[c:3]([NH2:17])[n:4][c:5](=[O:16])[n:6]([CH:7]2[CH2:8][CH:9]([OH:10])[CH:11]([CH2:12][O:13][Si:27]([C:23]([CH3:24])([CH3:25])[CH3:26])([CH3:28])[CH3:29])[O:14]2)[cH:15]1

Participants

5

Reactant 4

HCID 795ImidazoleHCID 6228DimethylformamideHCID 28928tert-Butyldimethylsilyl chlorideHCID 3525554-Amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

Product 1

HCID 577126895-TBDMS-5-I-2-dC

Sources & evidence

ORD record
ord-98b383bfa829463c9175eb43af4f466b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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