Dichloromethane → 7-(benzyloxy)-2,3,4,5-tetrahydro-1H-3-benzazepine

HRID 1540815Notes

Reaction equation

HRID 1540815 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][c:16]([O:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:17][cH:18]2)[CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[Cl:34][CH2:35][Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[NH:8]1[CH2:9][CH2:10][c:11]2[c:12]([cH:15][c:16]([O:19][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:17][cH:18]2)[CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 57437616tert-butyl 7-(benzyloxy)-1,2,4,5-tetrahydro-3H-benzo[d]azepine-3-carboxylate

Product 1

HCID 574376177-(benzyloxy)-2,3,4,5-tetrahydro-1H-3-benzazepine

Sources & evidence

ORD record
ord-06639a5d174e4259aca57229e99c2368
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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