Hydrochloric Acid → Hydrochloric Acid

HRID 1540925Notes

Reaction equation

HRID 1540925 reaction equation
[ClH:30].[NH2:1][c:2]1[n:3][c:4](-[c:23]2[c:24]([OH:29])[cH:25][cH:26][cH:27][cH:28]2)[cH:5][c:6]([CH:10]2[CH2:11][N:12]([C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])[CH2:13][CH2:14][CH2:15]2)[c:7]1[C:8]#[N:9].[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1>>[ClH:30].[NH2:1][c:2]1[n:3][c:4](-[c:23]2[c:24]([OH:29])[cH:25][cH:26][cH:27][cH:28]2)[cH:5][c:6]([CH:10]2[CH2:11][NH:12][CH2:13][CH2:14][CH2:15]2)[c:7]1[C:8]#[N:9]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 135550611Tert-butyl 3-[2-amino-3-cyano-6-(2-hydroxyphenyl)-4-pyridinyl]-1-piperidinecarboxylate

Product 2

HCID 313Hydrochloric AcidHCID 1354328582-Amino-6-(2-hydroxyphenyl)-4-(piperidin-3-yl)nicotinonitrile

Sources & evidence

ORD record
ord-ca65dc096cfe4207942f8f6ea230b0b6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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