5-chloro-1H-indole-2,3-dione → 3-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-methoxyphenyl]-5-chloro-3-hydroxy-1,3-dihydro-2H-indol-2-one

HRID 1541102Notes

Reaction equation

HRID 1541102 reaction equation
[Br:1][c:2]1[c:3]([O:17][CH3:18])[cH:4][c:5]([CH2:6][O:7][Si:8]([CH3:9])([CH3:10])[C:11]([CH3:12])([CH3:13])[CH3:14])[cH:15][cH:16]1.[Cl:19][c:20]1[cH:21][c:22]2[c:26]([cH:27][cH:28]1)[NH:25][C:24](=[O:29])[C:23]2=[O:30]>>[c:2]1([C:23]2([OH:30])[c:22]3[cH:21][c:20]([Cl:19])[cH:28][cH:27][c:26]3[NH:25][C:24]2=[O:29])[c:3]([O:17][CH3:18])[cH:4][c:5]([CH2:6][O:7][Si:8]([CH3:9])([CH3:10])[C:11]([CH3:12])([CH3:13])[CH3:14])[cH:15][cH:16]1

Participants

3

Reactant 2

HCID 872035-chloro-1H-indole-2,3-dioneHCID 67429327((4-Bromo-3-methoxybenzyl)oxy)(tert-butyl)dimethylsilane

Product 1

HCID 674298243-[4-({[tert-butyl(dimethyl)silyl]oxy}methyl)-2-methoxyphenyl]-5-chloro-3-hydroxy-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-3c652aa75eca4fa8b06e80556535249f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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