Hydrochloric Acid → 4-[3-(6-Methoxy-4-quinolinyl)-3-oxopropyl]-1-[3-(2,3,5-trifluorophenyl)-2-propyn-1-yl]-3-piperidinecarboxylic acid
Reaction equation
[C:41](=[O:42])([O-:43])[OH:44].[CH:46]([Cl:47])([Cl:48])[Cl:49].[ClH:39].[Na+:45].[O:1]=[C:2]([CH2:3][CH2:4][CH:5]1[CH:6]([C:23](=[O:24])[O:25][CH3:26])[CH2:7][N:8]([CH2:11][C:12]#[C:13][c:14]2[c:15]([F:22])[c:16]([F:21])[cH:17][c:18]([F:20])[cH:19]2)[CH2:9][CH2:10]1)[c:27]1[cH:28][cH:29][n:30][c:31]2[cH:32][cH:33][c:34]([O:37][CH3:38])[cH:35][c:36]12.[OH2:40]>>[O:1]=[C:2]([CH2:3][CH2:4][CH:5]1[CH:6]([C:23](=[O:24])[OH:25])[CH2:7][N:8]([CH2:11][C:12]#[C:13][c:14]2[c:15]([F:22])[c:16]([F:21])[cH:17][c:18]([F:20])[cH:19]2)[CH2:9][CH2:10]1)[c:27]1[cH:28][cH:29][n:30][c:31]2[cH:32][cH:33][c:34]([O:37][CH3:38])[cH:35][c:36]12Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-2361c152bbf947dd8539fb926579030d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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