Dichloromethane → 6-(2-Hydroxy-2-methylpropyl)-6-phenyl-3-piperidin-3-yl-1,3-oxazinan-2-one
Reaction equation
[Cl:39][CH2:40][Cl:41].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38].[OH:1][C:2]([CH2:3][C:4]1([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:5][CH2:6][N:7]([CH:11]2[CH2:12][N:13]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:14][CH2:15][CH2:16]2)[C:8](=[O:10])[O:9]1)([CH3:30])[CH3:31]>>[OH:1][C:2]([CH2:3][C:4]1([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:5][CH2:6][N:7]([CH:11]2[CH2:12][NH:13][CH2:14][CH2:15][CH2:16]2)[C:8](=[O:10])[O:9]1)([CH3:30])[CH3:31]Participants
4
Sources & evidence
- ORD record
- ord-8f6868395b4949b6bf9ea5a1dd06a8f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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