Tetrahydrofuran → Ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate

HRID 1541239Notes

Reaction equation

HRID 1541239 reaction equation
[N:19]([O:20][CH2:21][CH2:22][CH:23]([CH3:24])[CH3:25])=[O:26].[NH2:1][c:2]1[c:3]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:4][n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1>>[cH:2]1[c:3]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:4][n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([F:13])[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 8053Isoamyl NitriteHCID 688689ethyl 5-amino-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate

Product 1

HCID 14994516Ethyl 1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate

Sources & evidence

ORD record
ord-3227d87770a245d487d2ec1a9b39003b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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