Trifluoroacetic acid → 3-[2-(7-Bromo-4-oxo-4H-1,3-benzothiazin-2-yl)-4-pyridyl]propionic acid

HRID 1541369Notes

Reaction equation

HRID 1541369 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([c:6](=[O:25])[n:7][c:8](-[c:10]3[n:11][cH:12][cH:13][c:14]([CH2:16][CH2:17][C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:15]3)[s:9]2)[cH:26][cH:27]1.[OH:28][C:29]([C:30]([F:31])([F:32])[F:33])=[O:34]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([c:6](=[O:25])[n:7][c:8](-[c:10]3[n:11][cH:12][cH:13][c:14]([CH2:16][CH2:17][C:18](=[O:19])[OH:20])[cH:15]3)[s:9]2)[cH:26][cH:27]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 22939429tert-Butyl 3-[2-(7-bromo-4-oxo-4H-1,3-benzothiazin-2-yl)-4-pyridyl]propanoate

Product 1

HCID 597502103-[2-(7-Bromo-4-oxo-4H-1,3-benzothiazin-2-yl)-4-pyridyl]propionic acid

Sources & evidence

ORD record
ord-22775584c12a4c359d8bec00bbfb1db7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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