Pyridine → 5-Amino-1-(3,5-bis-trifluoromethyl-benzyl)-1H-imidazole-4-carbonitrile
Reaction equation
[NH2:1][c:2]1[c:3]([C:22](=[O:23])[NH2:24])[n:4][cH:5][n:6]1[CH2:7][c:8]1[cH:9][c:10]([C:18]([F:19])([F:20])[F:21])[cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1.[c:25]1([CH3:26])[cH:27][cH:28][c:29]([S:30]([Cl:31])(=[O:32])=[O:33])[cH:34][cH:35]1.[cH:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1>>[NH2:1][c:2]1[c:3]([C:22]#[N:24])[n:4][cH:5][n:6]1[CH2:7][c:8]1[cH:9][c:10]([C:18]([F:19])([F:20])[F:21])[cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]1Participants
4
Sources & evidence
- ORD record
- ord-45da4376a79246f2985eae20a7424a59
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…