Tetrahydrofuran → 1-[4-(1-Hydroxycyclopentyl)phenyl]cyclopropanecarboxylic acid
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[OH:13])[CH2:9][CH2:10]2)[cH:6][cH:7]1.[CH2:14]([Mg:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH2:20][CH2:21][CH3:22].[CH2:23]([Li:24])[CH2:25][CH2:26][CH3:27].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40].[O:28]=[C:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[c:2]1([C:29]2([OH:28])[CH2:30][CH2:31][CH2:32][CH2:33]2)[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[OH:13])[CH2:9][CH2:10]2)[cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-7078c229041b42bf9765c5936845572c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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