Dimethylformamide → 2-Chloro-5-nitropyridine-3-carboxylic acid

HRID 154208Notes

Reaction equation

HRID 154208 reaction equation
[CH3:14][N:15]([CH3:16])[CH:17]=[O:18].[OH:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([N+:11](=[O:12])[O-:13])[cH:9][n:10]1.[S:19]([Cl:20])([Cl:21])=[O:22]>>[c:2]1([Cl:21])[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([N+:11](=[O:12])[O-:13])[cH:9][n:10]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24386Thionyl ChlorideHCID 178524577HCID 178524577, compound

Product 1

HCID 125426642-Chloro-5-nitropyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-f0063a4d007f4d69bb32f5cd70a39b04
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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