Water → p-Toluenesulfonic acid

HRID 1542202Notes

Reaction equation

HRID 1542202 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]([C:14]#[N:15])[CH2:10][CH:11]([OH:13])[CH2:12]1)([CH3:5])([CH3:6])[CH3:7].[CH3:17][c:18]1[cH:19][cH:20][c:21]([S:24](=[O:25])(=[O:26])[OH:27])[cH:22][cH:23]1.[CH3:28][C:29]#[N:30].[OH2:16]>>[CH3:17][c:18]1[cH:19][cH:20][c:21]([S:24](=[O:25])(=[O:26])[OH:27])[cH:22][cH:23]1.[NH:8]1[CH:9]([C:14]#[N:15])[CH2:10][CH:11]([OH:13])[CH2:12]1

Participants

6

Reactant 4

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 6342AcetonitrileHCID 68626765Tert-butyl 2-cyano-4-hydroxy-pyrrolidine-1-carboxylate

Product 2

HCID 6101p-Toluenesulfonic acidHCID 233627304-Hydroxypyrrolidine-2-carbonitrile

Sources & evidence

ORD record
ord-f39ee653ce66444ebd8c9cc500563c11
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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